Research
Research in the Division of Cardiovascular and Medical Sciences involves both clinical and laboratory-based scientists.
The major focus for research in the Division is Cardiovascular Disease. Studies adopt a wide range of techniques, including genetic, molecular, cellular, physiological and clinical, with an emphasis on integrating approaches in a translational manner. There is a well established interest in the management of hypertension and treatment of cardiovascular diseases including clinical pharmacology of antihypertensive drugs and alternative approaches to the delivery and assessment of long term cardiovascular care. The majority of our research activity is based in the BHF Glasgow Cardiovascular Research Centre. This was opened in 2006, as a result of a generous donation by the British Heart Foundation and a fund raising effort by the University of Glasgow. The Centre houses internationally recognised cardiovascular research groups and provides a multidisciplinary research environment. It has state-of-the-art clinical research facilities, physiology and electrophysiology laboratories, well equipped molecular laboratories with facilities for human and experimental genetics, genomics and proteomics including high throughput SNP genotyping, gene expression profiling, vascular gene transfer/therapy and many other modern molecular technologies. There is a well equipped and fully staffed Clinical Research Facility within the Centre, jointly run with NHS Greater Glasgow and Clyde as part of the network of CRFs in the city. At present there are eight group leaders within the Centre, each with programme grant funding; there are approximately 150 research and technical staff in total.
Other current research within the Division includes development of novel biological markers (haematological, biochemical and electrophysiological) in cardiovascular disease and ageing. There is also extensive programme of research in stoke and cerebrovascular disease extending from acute stroke imaging and drug treatment (Based in the Western Infirmary) to rehabilitation and assessment of care pathways (in Glasgow Royal Infirmary). Other research groups work on exercise medicine which includes interests in performance athletes but also the use of exercise in assessment and management of common medical conditions. There are also groups with long-standing interests in drug treatment of epilepsy and the management of seizures in the community and upper gastrointestinal disease, including gastro-oesophageal reflux, peptic ulcer disease and gastric carcinoma.
Research Groups within the Division are:-
BHF Cardiovascular Research Group
PI- Professor Anna Dominiczak & Professor Andrew Baker
MRC Cardiovascular Research Group
PI- Professor John Connell & Professor Eleanor Davies
Heart Failure and Pharmacology Group
PI-Professor John McMurray
CVS & Renal Failure Research Group
PI- Professor Alan Jardine
Metabolic Medicine Research Group
PI- Professor Naveed Sattar
Cardiac Imaging Research Group
PI- Professor Godfrey Smith & Professor Stuart Cobbe
Stroke Medicine Research Group
PI- Professor Kennedy Lees
Geriatric Medicine Research Group
PI- Professor Peter Langhorne & Professor David Stott
Clinical Pharmacology Research Group
PI- Professor Gordon McInnes
Electrocardiology Research Group
PI- Professor Peter MacFarlane
Haemostasis and Thrombosis Research Group
PI- Professor Gordon Lowe
Gastroenterology Research Group
PI- Professor Ken McColl
Vascular Biochemistry Research Group
PI- Professor Muriel Caslake